Title
Novel design and fabrication of bone scaffold
Abstract
As for the acceleration of population ageing, paced-life speeding, and urban environment deteriorating, people suffer from bone defects caused by natural diseases, accidental injuries, and bone fracture amongst athletes resulting in bone defect treatment as a main clinical surgery. Artificial bone implants are greatly used to replace and fix injured or fractured bone, resulting in normal physiological functions. From the biological points of view, it should benefit from good biocompatibility, including blood compatibility and histocompatibility. In terms of mechanical properties, sufficient mechanical strength is a key parameter to ensure stable structural support in the body. Furthermore, bone implants should have an external contour that matches the defect’s anatomical structure as far as possible, avoiding excessive bone resection during implantation. A series of factors including mechanical properties, geometry, shape and size of porosity, etc play a pivotal role in this research area. This research intends to bridge up the gap between the current materials, design and manufacturing methods for biomedical implants.