51³Ô¹Ïapp

Mariasole obtained an undergraduate degree (BSc) and a Masters degree (MSc) in Sport and Exercise Science from the University of Bologna. In the same institution, she went on to complete a PhD in Exercise Physiology, focusing on the effects of endurance and interval training on cardiorespiratory and muscular parameters during exercise in healthy adults. After the PhD Mariasole worked as postdoctoral fellow at the University of Aberdeen on a BBSRC funded project investigating the effects of fish oil and resistance training on muscle mass and function in sarcopenic older people. Subsequently, she worked as KTP Research Associate at the University of Derby, before joining 51³Ô¹Ïapp in 2017 as Lecturer in Biomedical Science. 

Nutrition & Metabolic health

Biomedical and Environmental Health

- Festa J, Hussain A, Hackney A, Desai U, Sahota TS, Singh H, Da Boit M (2023). Elderberry extract improves molecular markers of endothelial dysfunction linked to atherosclerosis. Food Sci Nutr. May 10;11(7):4047-4059. doi: 10.1002/fsn3.3393

- Festa J, Singh H,  Hussain A, Da Boit M (2022). Elderberry extract inhibits tumour necrosis factor induced monocyte adhesion to endothelial cells via modulation of the NF-κB pathway, Cardiovascular Research, Volume 118, Issue Supplement. Doi: 10.1093/cvr/cvac066.172

- Da Boit M, Santos-Merx L (2021). Reduced-fat breakfast impact on appetite regulation in healthy adults: Views from a nutritional and psychological pilot study. Appetite 157:104915; DOI: 10.1016/j.appet.2020.104915  

- Carru C, Da Boit M, Paliogiannis P, Zinellu A, Sotgia S, Sibson R, Meakin JR, Aspden RM, Mangoni AA, Gray SR. Markers of oxidative stress, skeletal muscle mass and function, and their responses to resistance exercise training in older adults. Exp Gerontol. 2018 Mar;103:101-106. doi: 10.1016/j.exger.2017.12.024. Epub 2018 Jan 9. PMID: 29326089. 

- Da Boit M, Tommasi S, Elliot D, et al. Sex Differences in the Associations between L-Arginine Pathway Metabolites, Skeletal Muscle Mass and Function, and their Responses to Resistance Exercise, in Old Age. J Nutr Health Aging. 2018;22(4):534-540. doi:10.1007/s12603-017-0964-6

- Da Boit M, Sibson R, Sivasubramaniam S, Meakin JR, Greig CA, Aspden RM, Thies F, Jeromson S, Hamilton DL, Speakman JR, Hambly C, Mangoni AA, Preston T, Gray SR. Sex differences in the effect of fish-oil supplementation on the adaptive response to resistance exercise training in older people: a randomized controlled trial. Am J Clin Nutr. 2017 Jan;105(1):151-158. doi: 10.3945/ajcn.116.140780. Epub 2016 Nov 16. PMID: 27852617; PMCID: PMC5183731.

- Da Boit M, Sibson R, Meakin JR, et al. Sex differences in the response to resistance exercise training in older people. Physiol Rep. 2016;4(12):e12834. doi:10.14814/phy2.12834

For a full list of Dr Da Boit's publications please see 

- Festa J, Hussain A, Hackney A, Desai U, Sahota TS, Singh H, Da Boit M (2023). Elderberry extract improves molecular markers of endothelial dysfunction linked to atherosclerosis. Food Sci Nutr. May 10;11(7):4047-4059. doi: 10.1002/fsn3.3393

- Rowland SN, Da Boit M, Tan R, Robinson GP, O'Donnell E, James LJ, Bailey SJ (2022). Dietary Nitrate Supplementation Enhances Performance and Speeds Muscle Deoxyhaemoglobin Kinetics during an End-Sprint after Prolonged Moderate-Intensity Exercise. Antioxidants (Basel). Dec 23;12(1):25. doi: 10.3390/antiox12010025

- Da Boit M, Santos-Merx L (2021). Reduced-fat breakfast impact on appetite regulation in healthy adults: Views from a nutritional and psychological pilot study. Appetite 157:104915; DOI: 10.1016/j.appet.2020.104915  

- Da Boit M, Tommasi S, Elliot D, Zinellu A, Sotgia S, Sibson R, Meakin JR, Aspden RM, Carru C, Mangoni AA, Gray SR. Sex Differences in the Associations between L-Arginine Pathway Metabolites, Skeletal Muscle Mass and Function, and their Responses to Resistance Exercise, in Old Age. J Nutr Health Aging. 2018;22(4):534-540. doi: 10.1007/s12603-017-0964-6. PMID: 29582894.

-Da Boit M, Sibson R, Sivasubramaniam S, Meakin JR, Greig CA, Aspden RM, Thies F, Jeromson S, Hamilton DL, Speakman JR, Hambly C, Mangoni AA, Preston T, Gray SR. Sex differences in the effect of fish-oil supplementation on the adaptive response to resistance exercise training in older people: a randomized controlled trial. Am J Clin Nutr. 2017 Jan;105(1):151-158. doi: 10.3945/ajcn.116.140780. Epub 2016 Nov 16. PMID: 27852617; PMCID: PMC5183731.

- Da Boit M, Sibson R, Meakin JR, et al. Sex differences in the response to resistance exercise training in older people. Physiol Rep. 2016;4(12):e12834. doi:10.14814/phy2.12834

Mariasole is currently undertaking research in the following areas: 

- Influence of polyphenols supplementation on cardiovascular health and underpinning molecular mechanisms

- Nutritional and exercise interventions to improve skeletalmuscle health in different populations

- Physiological and psychological determinants of appetite regualtion 

Her research expertise includes:

• Human Anatomy and Physiology 
• Nutrition, enviroiment and public health 
• Diabetes and cardiovascular disease mechanisms and therapeutics 
• Research projects 

• Ph.D. in Exercise Physiology
• MSc in Preventive and Adapted Physical Activities
• BSc in Exercise and Sport Sciences
• PGCert in Teaching and Learning in Higher Education

• Medical Science (BMed Sci)
• Biomedical Science (BSc)
• Physician Associate (MSc)
• Advanced Biomedical Science (MSc)

Fellow of the Higher Education Academy (FHEA)

• The Physiological Society
• The Nutrition Society 

CMI certificate in Management and Leadership  

Postgraduate Certificate in Learning and Teaching in Higher Education (PGCLTHE)

- Festa J, Singh H, Hussain A, Da Boit M.  Elderberry, its major anthocyanin Cyanidin-3-glucoside, and phenolic metabolites prevent initial stages of atherosclerosis in vitro. International conference of Food Bioactive and Health. Parma, 21- 24 June 2022. 

- Hussain A, Festa J, Singh H, Da Boit M.  The cytoprotective effects of blackcurrant extract on endothelial cells via intracellular vesicular trafficking. International conference of Food Bioactive and Health. Parma, 21- 24 June 2022. 

- Da Boit M & Santos-Merx L. Reduced-fat breakfast impact on appetite regulation in healthy adults: Views from a nutritional and psychological pilot study. The British Feeding and Drinking Group. Liverpool, 14 - 15 April 2020.

• PhD, Mohammed Elhag

-  Health Tech Bio Actives, S.L.U. 2023- Influence of chronic supplementation with Cardiose hesperidin on nitric oxide biomarkers, cardiovascular and mitochondrial function, and exercise capacity in older adults.   £270,000  (Co-I) 

- Research Springboard Studentship funded by The Physiological Society 2022 - Broccoli and tuna: keys to unlocking Alzheimer’s mechanism?  £1,740

- MRes self-funded scholarship 2019 -  The effect of breakfast portion size on appetite perception and energy intake in adults.  £ 6,500

 - Fully funded PhD scholarship 2019 - The role of berries on endothelial dysfuntcion.  £45k 

- Blackcurrant extract and autophagy in HUVECs, 2018.  £5k

If you are interested in persuing a PhD or MRes under my supervision, please get in touch: mariasole.daboit@dmu.ac.uk